Effect of prostaglandin A(1), arsenite and aspirin on stress proteins response in mosquito cells

Authors
de Meneses, MDF Rebello, MA
Citation
Mdf. De Meneses et Ma. Rebello, Effect of prostaglandin A(1), arsenite and aspirin on stress proteins response in mosquito cells, Z NATURFO C, 56(3-4), 2001, pp. 298-302
Citations number
24
Categorie Soggetti
Biochemistry & Biophysics
Journal title
ZEITSCHRIFT FUR NATURFORSCHUNG C-A JOURNAL OF BIOSCIENCES
ISSN journal
09395075 → ACNP
Volume
56
Issue
3-4
Year of publication
2001
Pages
298 - 302
Database
ISI
SICI code
0939-5075(200103/04)56:3-4<298:EOPAAA>2.0.ZU;2-8
Abstract
The stress response of eukaryotic cells is characterized by changes in the metabolism of responding cells, most notably by increased synthesis of a gr oup of proteins known as heat shock (HSP) proteins. In this paper the effec t of prostaglandin A(1) (PGA(1)), arsenite and aspirin in Aedes albopictus cells was investigated. In cells treated with PGA(1) (10 mug/ml) we observe d the induction of several polypeptides with molecular masses of 87, 80, 70 , 57, 29 and 23 kDa. Immunoblot analysis revealed that arsenite induces a m arked synthesis of HSP70, and aspirin administered during the hyperthermic treatment caused a small increase of HSP70 synthesized.