O. Villegascabello et al., STAGED REPLACEMENT OF THE CANINE TRACHEA WITH RINGED POLYETHYLENE TEREPHTHALATE GRAFTS, The thoracic and cardiovascular surgeon, 42(5), 1994, pp. 302-305
The reconstruction of extensive defects of the trachea ist best accomp
lished by the use of the patient's own tissue. Unfortunately, this is
not always feasible and several prosthetic devices for replacement of
the tracheal have been described. In an experimental study staged trac
heal replacements were performed in five dogs using a ringed polyethyl
ene terephthalate (PET) tubular prosthesis previously cultured in the
major omentum of the subjects. A set of stainless-steel arches embodie
d in silicone compound was designed to prevent collapse of the prosthe
sis. One of the subjects died on the 10th post-operative day of an uni
dentified cause and the remaining four eventually developed signs of r
espiratory distress. The cause of the respiratory insufficiency was an
astomotic stenosis in every case. Infection, erosion, collapse or disp
lacement were not observed. The rings designed to avoid collapse of th
e prosthesis represent a suitable alternative for use as external rein
forcement in the tracheal situation. The PET grafts implanted as trach
eal prosthesis according to the guidelines of this protocol consistent
ly developed anastomotic stenosis and failed to support a functional r
espiratory epithelium. A further conclusion is that the use of absorba
ble sutures encourages anastomotic dehiscence and thus must be avoided
.