Refraction in juvenile chronic arthritis: a long-term follow-up study, with emphasis on myopia

Objective: Assessment of refraction anomalies in juvenile chronic arthritis (JCA) on a long-term follow-up basis Material and Methods: Sixty-five adults 52 females and 13 males, with a his tory of active JCA had a complete ophthalmic evaluation including subjectiv e refractioning on average 26.4 years after JCA onset. The age range was 22 -49 years. Results: The refraction ranged from -8.12 D to +6.5 D with a mean (SD) of - 0.64 (2.16) D, The mean refraction in the JCA group was significantly more towards myopia than that of a coeval adult hospital-based sample used as co ntrols (p = 0.008), Twenty-eight out of the 65 (43%) had a negative refract ive value of at least 0.37 D, Myopia onset age ranged from 8 to 31 years In those able to specify their myopia onset by first purchase of spectacles ( n = 25) the JCA onset had preceded the myopia, with a mean (SD) interval of 10.1 (5.4) years. Conclusion: The elevated myopia figure of 43% among JCA patients suggests a n association between myopia and JCA, In lack of more precise indicators an d in accordance with older literature, an explanation might be a weakening effect of chronic inflammation on scleral connective tissue.