The Val(606)Met mutation in the cardiac beta-myosin heavy chain gene in patients with familial hypertrophic cardiomyopathy is associated with a high risk of sudden death af young age

Authors
Havndrup, O Bundgaard, H Andersen, PS Larsen, LA Vuust, J Kjeldsen, K Christiansen, M
Citation
O. Havndrup et al., The Val(606)Met mutation in the cardiac beta-myosin heavy chain gene in patients with familial hypertrophic cardiomyopathy is associated with a high risk of sudden death af young age, AM J CARD, 87(11), 2001, pp. 1315-1317
Citations number
20
Categorie Soggetti
Cardiovascular & Respiratory Systems","Cardiovascular & Hematology Research
Journal title
AMERICAN JOURNAL OF CARDIOLOGY
ISSN journal
00029149 → ACNP
Volume
87
Issue
11
Year of publication
2001
Pages
1315 - 1317
Database
ISI
SICI code
0002-9149(20010601)87:11<1315:TVMITC>2.0.ZU;2-3
Abstract
A study of published families disclosed that the Val(606)Met mutation in P- myosin heavy chain carries a high risk of sudden death at a young age. The association of a specific mutation with a certain phenotype should be based on a large number of families to avoid sampling bias.