In summary, postprandial lipemia after a high-fat meal was not associated,v
ith an impairment in endothelium-dependent, how-mediated vasodilation of th
e brachial artery in young healthy women. These data are at variance with p
revious findings in young healthy men,g and allow one to conclude that a st
rong gender-related difference exists in the susceptibility to vascular eff
ects of postprandial lipemia in young subjects. This gender difference may
be 1 basic mechanism underlying the lower susceptibility to coronary heart
disease events observed in premenopausal women than in age-matched men.