Occupational categories at risk for Parkinson's disease

Citation
Kl. Kirkey et al., Occupational categories at risk for Parkinson's disease, AM J IND M, 39(6), 2001, pp. 564-571
Citations number
20
Categorie Soggetti
Envirnomentale Medicine & Public Health
Journal title
AMERICAN JOURNAL OF INDUSTRIAL MEDICINE
ISSN journal
02713586 → ACNP
Volume
39
Issue
6
Year of publication
2001
Pages
564 - 571
Database
ISI
SICI code
0271-3586(200106)39:6<564:OCARFP>2.0.ZU;2-N
Abstract
Background The etiology of Parkinson's disease (PD) is considered to have a strong environmental component, but relatively few studies have investigat ed the potential association between occupation and the disease. Methods In a population-based case-control study we collected collected com prehensive occupational histories from all study participants, 144 case and 464 control subjects. Results Chi-square analysis revealed that working in an agricultural occupa tion increased estimated PD risk (OR = 1.74; 95% CI = 0.85, 3.60). In contr ast, a history of ever working in a service occupation was negatively assoc iated with PD risk (OR = 0.69; 95% CI = 0.47, 1.00). Risk estimates were cl ose to one for specific service occupations. Adjusted odds ratios for all n on-service occupational and industrial categories were similar, and working in a service occupation was the only significant inverse predictor of PD r isk. Conclusions Future investigations focusing on lifestyle factors mid environ mental exposures within the agricultural and service occupational categorie s are warranted. Am. J. Ind. Med. 39:564-571, 2001. (C) 2001 Wiley-Liss, In c.