Failure to find the gallbladder at the usual or most common atypical s
ites during surgery for cholecystolithiasis is a rare but known proble
m. Although ultrasonography has 95 % sensitivity for the diagnosis of
cholelithiasis, occasionally a small contracted gallbladder with stone
s and chronic cholecystitis will be difficult to visualize and can lea
d to erroneous interpretation. We report on the case of a patient pres
enting with abdominal colic and ultrasonographically confirmed cholecy
stolithiasis. During laparoscopic cholecystectomy, the gallbladder cou
ld not be detected, After laparoscopic staging followed by endoscopic
retrograde cholangiopancreatography and abdominal computed tomography,
agenesis of the gallbladder was confirmed. This method can be conside
red for diagnosis of gallbladder agenesis without the need for laparot
omy and thorough exploration.