Dielectrical model of cellular structures in radio frequency and microwavespectrum. Electrically interacting versus noninteracting cells

A model of dielectrical properties of cellular structures of a tissue has b een proposed. Cellular structures were presented as a composition of membra ne covered spheres and cylinders that do not interact with each other. No r estrictions were applied to the thickness of cellular membranes. The model was further generalized into a case of electrically interacting cells. The difference in dielectrical properties calculated with the model of electric ally noninteracting versus interacting cells is inversely dependent on freq uency. At biological values of cellular volume fraction near 0.7 (packed co nfiguration) the difference is about 10%-15% in resistance and in epsilon ' for frequencies near 0.1 MHz. Experimental data for myocardial tissue and theoretical data, for both interacting and noninteracting models, reasonabl y agree at frequencies of 1-100 MHz. (C) 2001 Biomedical Engineering Societ y.