The aim of this study was to assess the use of Tc-99m tetrofosmin (Tc-TF) s
cintigraphy for detecting malignant lymphomas. In the study, before any che
motherapy, 50 patients with malignant lymphoma underwent Tc-TF scintigraphy
, which was performed 10 minutes after intravenous injection of 20 mCt Tc-T
F Tc-TF scintigraphy detected malignant lymphoma in 44 (88%) patients. Howe
ver, there were no significant differences in the incidences of positive an
d negative Tc-TF scintigraphic results between female versus male patients,
HD versus NHL patients, stage I-II versus stage III-IV patients, age > 40
years versus less than or equal to 40 years patients and patients with B sy
mptoms false-negative results occured in 4 (8%) infradiaphragmatic malignan
t lymphoma. We conclude patients with that Tc-TF scintigraphy appears suita
ble for detecting malignant lymphoma, especially supradiaphragmatic lesions
.