Objective: To compare flavoring agents added to activated charcoal (AC) to
determine which mixture is most palatable to children.
Design: Healthy volunteers between the ages of 3 and 17 years participated
in a prospective masked trial. Five identical pitchers were prepared contai
ning AC alone, AC with chocolate milk, AC with Coca-Cola (Coca-Cola Corp, A
tlanta, Ga), AC with cherry-flavored syrup, and AC with sorbitol. Subjects
tasted all S substances in random order. Children younger than 8 years rate
d taste on a 10-point Faces Scale. Children 8 years and older used a 100-po
int visual analog scale to rate taste and, separately, ease of swallowing.
All children were asked which mixture was best. Ratings were compared using
1-way analysis of variance, and comparisons for all pairs were made using
the Tukey test. P < .05 was considered significant.
Results: Mean age among the 53 children enrolled was 8.3 years; 23 children
were younger than 8 years. Girls made up 52% of the group. Taste scores fo
r chocolate milk, Coca-Cola, and cherry-flavored syrup were significantly b
etter than those for no flavoring agent. The scores for ease of swallowing
for Coca-Cola, chocolate milk, and cherry-flavored syrup were significantly
better than those for either no flavoring agent or sorbitol. When asked to
choose a single best flavoring agent, 39% chose chocolate milk, 23% picked
Coca-Cola, and 23% chose cherry-flavored syrup.
Conclusion: The addition of chocolate milk, Coca-Cola, or cherry-flavored s
yrup to AC improves palatability for children and is favored over no flavor
ing agent or sorbitol.