6,6 '-Bis(2-hydroxyphenyl)-2,2 '-bipyridine manganese(III) complexes: A novel series of superoxide dismutase and catalase mimetics

Authors
Giblin, GMP Box, PC Campbell, IB Hancock, AP Roomans, S Mills, GI Molloy, C Tranter, GE Walker, AL Doctrow, SR Huffman, K Malfroy, B
Citation
Gmp. Giblin et al., 6,6 '-Bis(2-hydroxyphenyl)-2,2 '-bipyridine manganese(III) complexes: A novel series of superoxide dismutase and catalase mimetics, BIOORG MED, 11(11), 2001, pp. 1367-1370
Citations number
18
Categorie Soggetti
Chemistry & Analysis
Journal title
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN journal
0960894X → ACNP
Volume
11
Issue
11
Year of publication
2001
Pages
1367 - 1370
Database
ISI
SICI code
0960-894X(20010604)11:11<1367:6''MCA>2.0.ZU;2-N
Abstract
A series of novel manganese(III) complexes is described based on a 6,6'-bis (2-hydroxyphenyl)-2,2'-bipyridine template. These complexes show superoxide dismutase and catalase activity. The effect of the aromatic substitution p attern on the SAR is described. (C) 2001 Elsevier Science Ltd. All rights r eserved.