Objects: The goal of this study was to investigate the differences between
clinical findings in youth and in adulthood on microvascular decompression
(MVD) of the facial nerve for the treatment of hemifacial spasm (HFS). Meth
ods: We retrospectively evaluated 855 patients who underwent MVD from Janua
ry 1985 to July 1999. In our series of 33 young HFS patients, all patients
had definite offending vessels. Interestingly, pathologic tortuous vertebra
l artery as a possible etiology was more rarely observed in young HFS patie
nts (1/33 patients, 3.0%) than in adult patients (61/822 patients, 7.4%) (P
<0.05). We did not observe any anatomical variations of the vessels or any
arachnoidal thickening around the root entry zone and cerebellopontine cist
ern in youths. Furthermore, young HFS patients did not necessarily have poo
rer surgical outcomes than adult HFS patients. Conclusions: Our results sug
gest that the cause and progress of HFS are the same in youth as in adultho
od, even though the pathogenesis of early onset remains unclear.