Forty-three consecutive patients who did not have healing of tibial or femo
ral diaphyseal and metaphyseal fractures and osteotomies for at least 9 mon
ths after injury or surgery were examined prospectively for use of high-ene
rgy extracorporeal shock waves. Former treatment modalities (cast, external
fixator, plate osteosynthesis, limitation of weightbearing) remained uncha
nged. In all cases a (99m)Technetium dicarboxyphosphonate regional two-phas
e bone scintigraphy was performed before one treatment with 3000 impulses o
f an energy flux density of 0.6 mJ/mm(2). Radiologic and clinical followups
were done at 4-week intervals starting 8 weeks after shock wave treatment.
The success criterion was bridging of all four cortices in the anteroposte
rior and lateral radiographic views, in oblique views, or by conventional t
omography, An independent observer described bony consolidation in 31 of 43
cases (72%) after an average of 4 months (range, 2-7 months). Twenty-nine
of 35 (82.9%) patients with a positive bone scan had healing of the pseudar
throsis compared with two of eight (25%) patients with a negative bone scan
. Six of these eight patients with negative scans were heavy smokers. No co
mplications were observed. High-energy shock wave therapy seemed to be an e
ffective noninvasive tool for stimulation of bone healing in properly selec
ted patients with a diaphyseal or metaphyseal nonunion of the femur or tibi
a, Additional controlled studies are mandatory.