Molecular motors: Kinesin's string variable

Authors
Citation
Ra. Cross, Molecular motors: Kinesin's string variable, CURR BIOL, 11(4), 2001, pp. R147-R149
Citations number
13
Categorie Soggetti
Experimental Biology
Journal title
CURRENT BIOLOGY
ISSN journal
09609822 → ACNP
Volume
11
Issue
4
Year of publication
2001
Pages
R147 - R149
Database
ISI
SICI code
0960-9822(20010220)11:4<R147:MMKSV>2.0.ZU;2-C
Abstract
A recent model suggests that the walking action of kinesin is due to a 13 r esidue 'fundamental engine' called the neck linker domain, which cyclically zips and unzips to the main part of the heads. New experiments confirm one prediction of the model: that crosslinking the neck linker to the head sho uld block motility,