mRNA quality control: Marking the message for life or death

Authors
Lykke-Andersen, J
Citation
J. Lykke-andersen, mRNA quality control: Marking the message for life or death, CURR BIOL, 11(3), 2001, pp. R88-R91
Citations number
29
Categorie Soggetti
Experimental Biology
Journal title
CURRENT BIOLOGY
ISSN journal
09609822 → ACNP
Volume
11
Issue
3
Year of publication
2001
Pages
R88 - R91
Database
ISI
SICI code
0960-9822(20010206)11:3<R88:MQCMTM>2.0.ZU;2-S
Abstract
A protein complex deposited upstream of exon-exon junctions after pre-mRNA splicing may serve a dual role in mRNA quality control by directing mRNA nu clear export and, possibly, serving as a downstream 'mark' for nonsense-med iated decay.