Neural transplantation therapies for Parkinson's and Huntington's diseases

Citation
Ra. Barker et Ae. Rosser, Neural transplantation therapies for Parkinson's and Huntington's diseases, DRUG DISC T, 6(11), 2001, pp. 575-582
Citations number
61
Categorie Soggetti
Pharmacology & Toxicology
Journal title
DRUG DISCOVERY TODAY
ISSN journal
13596446 → ACNP
Volume
6
Issue
11
Year of publication
2001
Pages
575 - 582
Database
ISI
SICI code
1359-6446(20010601)6:11<575:NTTFPA>2.0.ZU;2-X
Abstract
Parkinson's and Huntington's diseases are progressive neurodegenerative dis orders of the central nervous system for which symptomatic but not curative therapies are available. Therapeutic strategies have been developed to try and repair the brain in these conditions, including the use of grafts of f oetal neural tissue. Here, we consider the merits of this approach and disc uss the extent to which neural transplantation has successfully been transl ated into clinical studies for these diseases.