This paper gives a construction of braid group actions on the derived categ
ory of coherent sheaves on a variety X. The motivation for this is M. Konts
evich's homological mirror conjecture, together with the occurrence of cert
ain braid group actions in symplectic geometry. One of the main results is
that when dim X greater than or equal to 2, our braid group actions are alw
ays faithful.
We describe conjectural mirror symmetries between smoothings and resolution
s of singularities which lead us to find examples of braid group actions ar
ising from crepant resolutions of various singularities. Relations with the
McKay correspondence and with exceptional sheaves an Fano manifolds are gi
ven. Moreover the case of an elliptic curve is worked out in some detail.