J. Bratel et al., POTENTIAL SIDE-EFFECTS OF DENTAL AMALGAM RESTORATIONS .1. AN ORAL ANDMEDICAL INVESTIGATION, European journal of oral sciences, 105(3), 1997, pp. 234-243
The aim of this study was to explore a possible association between he
alth status and self-reported adverse effects related to dental amalga
m restorations. A group of 50 consecutive patients (index group), refe
rred for complaints self-related to dental amalgam restorations, was c
ompared with a control group of individuals matched by age, sex and po
stal zip code. The patients underwent an oral, stomatognathic, medical
and clinical chemistry examination. Mercury levels were examined in b
lood, urine and hair. The results revealed that somatic diseases were
more common in the index group (38% versus 6%). Symptoms related to cr
anio-mandibular dysfunction were reported by 74% of the patients in th
e index group versus 24% in the control group, and were diagnosed in 6
2% and 36%, respectively. The oral health status and the number of ama
lgam surfaces were similar in the 2 groups. No positive skin patch tes
t to mercury was found in any of the groups. The estimated mercury int
ake from fish consumption, occupational exposure, and mercury levels i
n blood and urine were also similar and far below levels, where negati
ve health effects would be expected. The correlation between the numbe
r of amalgam surfaces and mercury levels in plasma and urine (r = 0.43
) indicated a release of mercury from dental amalgam restorations in b
oth groups. Since the mercury levels were similar among index patients
and controls, mercury was not a likely cause of the impaired health r
eported by the patients.