Quantitative bacillary response to treatment in Mycobacterium tuberculosisinfected and M-africanum infected adults with pulmonary tuberculosis

Authors
Joloba, ML Johnson, JL Namale, A Morrissey, A Assegghai, AE Rusch-Gerdes, S Mugerwa, RD Ellner, JJ Eisenach, KD
Citation
Ml. Joloba et al., Quantitative bacillary response to treatment in Mycobacterium tuberculosisinfected and M-africanum infected adults with pulmonary tuberculosis, INT J TUBE, 5(6), 2001, pp. 579-582
Citations number
12
Categorie Soggetti
Cardiovascular & Respiratory Systems
Journal title
INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE
ISSN journal
10273719 → ACNP
Volume
5
Issue
6
Year of publication
2001
Pages
579 - 582
Database
ISI
SICI code
1027-3719(200106)5:6<579:QBRTTI>2.0.ZU;2-H
Abstract
Data regarding possible differences in microbiological response to therapy of disease caused by Mycobacterium tuberculosis and M. africanum are limite d. Presenting clinical characteristics and sputum bacillary load during sta ndard short-course chemotherapy in patients with newly-diagnosed pulmonary tuberculosis due to M. tuberculosis (n = 7) and M. africanum (n = 6) were c ompared. Changes in sputum bacillary load were measured using quantitative acid-fast bacilli smears, colony forming unit assay, and time until positiv e culture in the BACTEC((R)) radiometric system. Presentation and response to short course chemotherapy were comparable between patients infected with M. tuberculosis and those infected with M. africanum.