Noninvasive assessment of pulmonary arterial hypertension by MR phase-mapping method

We describe a magnetic resonance (MR) imaging method that emphasizes pressu re wave velocity to noninvasively assess pulmonary arterial hypertension. B oth the blood flow and the corresponding vessel cross-sectional area (CSA) were measured by MR phase mapping in the main pulmonary artery (MPA) in 15 patients. MPA pressures were also measured, in the same patients, by right- side heart catheterization. Two significant relationships were established: 1) between the pressure wave velocity in the MPA and the mean pressure in the MPA (Ppa) writing pressure wave velocity = 9.25 Ppa - 202.51 (r = 0.82) and 2) between the ratio of pressure wave velocity to the systolic blood v elocity peak in the MPA (R) and the mean pressure in the MPA writing R = 0. 68 Ppa - 4.33 (r = 0.89). Using these relationships, we estimated two press ure values to frame the actual Ppa value in each patient from the present s eries with a reasonable reliability percentage (87%).