Sildenafil (Viagra) facilitates weaning of inhaled nitric oxide following placement of a biventricular-assist device

Authors
Mychaskiw, G Sachdev, V Heath, BJ
Citation
G. Mychaskiw et al., Sildenafil (Viagra) facilitates weaning of inhaled nitric oxide following placement of a biventricular-assist device, J CLIN ANES, 13(3), 2001, pp. 218-220
Citations number
9
Categorie Soggetti
Aneshtesia & Intensive Care
Journal title
JOURNAL OF CLINICAL ANESTHESIA
ISSN journal
09528180 → ACNP
Volume
13
Issue
3
Year of publication
2001
Pages
218 - 220
Database
ISI
SICI code
0952-8180(200105)13:3<218:S(FWOI>2.0.ZU;2-I
Abstract
Sildenafil is a selective phosphodiesterase type 5 inhibitor used in the tr eatment of erectile dysfunction. We report the use of sildenafil to blunt t he rebound pulmonary hypertension seen following withdrawal of inhaled nitr ic oxide (NO) and milrinone. The relatively long duration of sildenafil's a ction on pulmonary artery pressures and lack of systemic hemodynamic effect make it an attractive option to facilitate weaning of inhaled NO. (C) 2001 by Elsevier Science Inc.