L. Fraenkel et Dt. Felson, Rheumatologists' attitudes toward routine screening for hydroxychloroquineretinopathy, J RHEUMATOL, 28(6), 2001, pp. 1218-1221
Objective. To examine rheumatologists' attitudes toward routine ophthalmolo
gic screening for hydroxychloroquine (HCQ) retinopathy and to estimate the
acceptability of hypothetical guidelines discouraging this practice.
Methods. We E-mailed a random sample of 300 US rheumatologists listed in th
e American College of Rheumatology (ACR) Directory who treat adults. We ask
ed about current screening practice, reasons for screening, and the effect
of hypothetical guidelines discouraging routine screening on future practic
e. Associations between adherence to guidelines and clinical variables were
evaluated using multiple logistic regression.
Results. Of 56% who responded, almost all (94%) currently screen their pati
ents at least once per year. Seventy-five percent stated that they would co
ntinue to screen because they are unwilling to accept ally risk of visual l
oss among their patients; 74% would continue to screen because of legal lia
bility; and 56% felt their patients would insist on being screened regardle
ss of their physician's opinion. Forty-four percent stated that they would
continue to screen regularly, even if the ACR published guidelines discoura
ging routine screening. Rheumatologists unwilling to accept any risk of ret
inopathy were less likely to follow guidelines discouraging screening (46 v
s 77%, adjusted OR 0.2, 95% CI 0.1-0.6), Patient insistence and fear of leg
al liability were not significantly associated with predicted adherence to
guidelines.
Conclusion. Our survey indicates that the majority of rheumatologists curre
ntly routinely screen their patients for HCQ retinopathy, and that many wou
ld not follow ACR guidelines discouraging this practice, at least in part b
ecause they are unwilling to accept any risk of visual damage.