Clinical effects of glucosamine hydrochloride diet for dry skin

A placebo-control double-blind study of long-term intake of glucosamine hyd rochloride (1 500 mg/day for 6 weeks) was conducted in 32 women who usually tend to have dry and rough skin. The following findings were obtained: (1) Examination by dermatologists indicated that glucosamine hydrochloride sig nificantly improved dryness of the skin, easiness to apply make-up, and exf oliation. (2) Determination of the moisture content in the skin revealed th at glucosamine hydrochloride increased the moisture content in the skin. (3 ) Microscopic skin surface analysis showed that glucosamine hydrochloride i mproved smoothness and scaliness of the skin. These findings suggested that long-term intake of glucosamine hydrochloride is effective in improving mo isture content and smoothness of the skin.