Plants cannot move to escape environmental challenges. Biotic stresses resu
lt from a battery of potential pathogens: fungi, bacteria, nematodes and in
sects intercept the photosynthate produced by plants, and viruses use repli
cation machinery at the host's expense. Plants, in turn, have evolved sophi
sticated mechanisms to perceive such attacks, and to translate that percept
ion into an adaptive response. Here, we review the current knowledge of rec
ognition-dependent disease resistance in plants. We include a few crucial c
oncepts to compare and contrast plant innate immunity with that more common
ly associated with animals. There are appreciable differences, but also sur
prising parallels.