Reorganisation of the sensorimotor cortex after early focal brain lesion: a functional MRI study in monozygotic twins

Citation
G. Cioni et al., Reorganisation of the sensorimotor cortex after early focal brain lesion: a functional MRI study in monozygotic twins, NEUROREPORT, 12(7), 2001, pp. 1335-1340
Citations number
25
Categorie Soggetti
Neurosciences & Behavoir
Journal title
NEUROREPORT
ISSN journal
09594965 → ACNP
Volume
12
Issue
7
Year of publication
2001
Pages
1335 - 1340
Database
ISI
SICI code
0959-4965(20010525)12:7<1335:ROTSCA>2.0.ZU;2-N
Abstract
Sensorimotor cortical reorganization after early brain lesions was studied by means of fMRI in two pairs of monozygotic twins, in each of which one me mber had a focal brain injury. This offered a unique opportunity to reduce the wide intersubject variability of the controls often found in similar st udies. Activation images were acquired during a motor task (sequential oppo sition finger movements) and a sensory task (passive brushing of palm and f ingers). During the tasks with the recovered hand, constant findings in the lesioned subjects were the activation of the undamaged areas adjacent to l esion site and the activation of the ipsilateral sensorimotor cortex. Bilat eral activation of the primary sensorimotor cortex was never observed in th e healthy co-twin controls. NeuroReport 12:1335-1340. (C) 2001 Lippincott W illiams & Wilkins.