In our university cardiac center, the incidence of a cohort of children wit
h acute neurologic complications resulting from cardiac catheterization per
formed for acyanotic or cyanotic congenital heart disease is 0.38% (14 chil
dren of a total of 3,648 catheterization procedures), Neurologic complicati
ons consisted of convulsion (n = 10), stroke (n = 6), intracranial hemorrha
ge (n = 2), extrapyramidal features (n = 1), paraplegia (n = 1), visual imp
airment (n = 1), hearing impairment (n = 1), and brachial plexus injury (n
= 1), The main risk factors included prolonged duration of catheterization
procedure and interventional manipulation in addition to cardiac catheteriz
ation, The possible mechanisms causing brain injury included cerebral embol
ism from local clots and hypoxia resulting from complications during the pr
ocedure. Other complications included intracranial hemorrhage secondary to
anticoagulation and peripheral plexopathy because of prolonged fixed postur
e during anesthesia. The prognosis for the majority of patients with stroke
is good. Neurologic sequelae, such as global developmental delay or epilep
sy, occurred in those with hypoxic-ischemic encephalopathy. (C) 2001 by Els
evier Science Inc. All rights reserved.