Concordance of deficit and non-deficit subtypes in siblings affected with schizophrenia

Authors
Fouldrin, G Jay, M Bonnet-Brilhault, F Menard, JF Petit, M Thibaut, F
Citation
G. Fouldrin et al., Concordance of deficit and non-deficit subtypes in siblings affected with schizophrenia, PSYCHIAT R, 102(1), 2001, pp. 59-64
Citations number
31
Categorie Soggetti
Psychiatry,"Neurosciences & Behavoir
Journal title
PSYCHIATRY RESEARCH
ISSN journal
01651781 → ACNP
Volume
102
Issue
1
Year of publication
2001
Pages
59 - 64
Database
ISI
SICI code
0165-1781(20010510)102:1<59:CODANS>2.0.ZU;2-7
Abstract
Deficit and non-deficit subtypes were examined for their concordance in 83 sibling pairs of 109 schizophrenic patients belonging to 46 multiply affect ed families. Using a sib-pair method, we have found that the distribution o f deficit and non-deficit syndromes in sibling pairs of schizophrenic patie nts differed significantly from chance expectation. This familial aggregati on suggests that the syndrome may be used to define phenotypes for genetic studies. (C) 2001 Etsevier Science Ireland Ltd. All rights reserved.