Epithelial cells in the peripheral blood of patients with cancer of the head and neck: incidence, detection and possible clinical significance

Authors
Pajonk, F Schlessmann, S Guttenberger, R Henke, M
Citation
F. Pajonk et al., Epithelial cells in the peripheral blood of patients with cancer of the head and neck: incidence, detection and possible clinical significance, RADIOTH ONC, 59(2), 2001, pp. 213-217
Citations number
31
Categorie Soggetti
Radiology ,Nuclear Medicine & Imaging","Onconogenesis & Cancer Research
Journal title
RADIOTHERAPY AND ONCOLOGY
ISSN journal
01678140 → ACNP
Volume
59
Issue
2
Year of publication
2001
Pages
213 - 217
Database
ISI
SICI code
0167-8140(200105)59:2<213:ECITPB>2.0.ZU;2-R
Abstract
In this study amplification of cytokeratin-19 mRNA by Reverse transcriptase -polymerase chain reaction (RT-PCR) was used to detect circulating tumor ce lls in the peripheral blood of patients with cancer of the head and neck be fore, during and after radiation therapy. Detection of cytokeratin-19-posit ive cells coincided with local failure, distant metastasis and anemia. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.