Cytodiagnosis of a meningeal fibrosarcoma metastatic to the thyroid gland

A case of primary leptomeningeal fibrosarcoma metastatic to the thyroid gla nd, diagnosed by fine needle aspiration biopsy is described. The patient, a 39-year-old women was initially diagnosed with a leptomeningeal fibrosarco ma. Sections of the primary tumor studied by electron microscopy showed tha t the tumor cells have the ultrastructure features of a fibroblast, She und erwent tumor resection, followed by chemotherapy and local radiotherapy. Fo ur months later, she presented with dysphagia. Ultrasonography confirmed th e presence of a 2-cm mass in the right lobe of thyroid. A fine needle aspir ation biopsy was performed. Light microscopy showed interwoven bundles of n eoplastic spindle cells similar to the primary tumor, consistent with a met astatic fibrosarcoma, To our knowledge, this is the first report of a prima ry meningeal fibrosarcoma that metastasized to the thyroid gland, which was diagnosed by a fine needle aspiration biopsy. Copyright (C) 2001 by W.B. S aunders Company.