Study Design: Review of cases.
Objective: To review cases of brucellosis in order to clarify diagnostic gu
idelines, treatment regimes and prognsis.
Setting: University Hospital, Turkey.
Methods: Study of 11 patients (9 male, 2 female) with either brucellar spon
dylitis or epidural brucellar abscess. Diagnosis made on clinical presentat
ion, laboratory findings, radiographic evidence and a minimum brucellar ant
i body of 1:160, a positive bacteriological culture and/ or histological fi
nding of inflammation of granulomatous tissue. All patients were treated wi
th a combination of oral antibiotics. Surgery was performed in 8 patients.
Results: At least 6 months antibiotic therapy using Rifampicin and Doxycycl
ine is recommended. Surgery is indicated in the presence of spinal instabil
ity, cord compression or radiculopathy. In our series eight patients requir
ed surgery.
Conclusion: The patients complaining of back pain, particularly in endemic
areas should be University Hospital, Turkey. Study of II patients (9 male,
2 female) with either brucellar spondylitis or epidural investigated as pos
sible cases of brucellosis.