Bismuth(III)-catalyzed synthesis of dihydropyrimidinones : Improved protocol conditions for the Biginelli reaction

Authors
Ramalinga, K Vijayalakshmi, P Kaimal, TNB
Citation
K. Ramalinga et al., Bismuth(III)-catalyzed synthesis of dihydropyrimidinones : Improved protocol conditions for the Biginelli reaction, SYNLETT, (6), 2001, pp. 863-865
Citations number
27
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNLETT
ISSN journal
09365214 → ACNP
Issue
6
Year of publication
2001
Pages
863 - 865
Database
ISI
SICI code
0936-5214(200106):6<863:BSOD:I>2.0.ZU;2-K
Abstract
An efficient synthesis of 3,4-dihydropyrimidines using bismuth chloride as a catalyst from an aldehyde, beta -keto ester and urea in acetonitrile is d escribed. Compared to the classical Biginelli reaction conditions, this new method consistently has the advantage of good yields (56-97%).