Synthesis of alkyl-substituted pyrroles by three-component coupling of carbonyl compound, amine and nitro-alkane/alkene on a solid surface of silica gel/alumina under microwave irradiation
Bc. Ranu et A. Hajra, Synthesis of alkyl-substituted pyrroles by three-component coupling of carbonyl compound, amine and nitro-alkane/alkene on a solid surface of silica gel/alumina under microwave irradiation, TETRAHEDRON, 57(22), 2001, pp. 4767-4773
Efficient synthesis of highly substituted alkylpyrroles and fused pyrroles
has been achieved by a three-component coupling of (a) alpha,beta -unsatura
ted aldehyde/ketone, amine and nitroalkane and (b) alpha,beta -unsaturated
nitroalkene, aldehyde/ketone and amine on the surface of silica gel and alu
mina without any solvent under microwave irradiation. (C) 2001 Elsevier Sci
ence Ltd. All rights reserved.