alpha-(trifluoromethyl)ethenyl boronic acid as a useful trifluoromethyl containing building block. Preparation and palladium-catalysed coupling with aryl halides

Authors
Jiang, B Wang, QF Yang, CG Xu, M
Citation
B. Jiang et al., alpha-(trifluoromethyl)ethenyl boronic acid as a useful trifluoromethyl containing building block. Preparation and palladium-catalysed coupling with aryl halides, TETRAHEDR L, 42(24), 2001, pp. 4083-4085
Citations number
15
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
24
Year of publication
2001
Pages
4083 - 4085
Database
ISI
SICI code
0040-4039(20010611)42:24<4083:ABAAAU>2.0.ZU;2-B
Abstract
alpha-(Trifluoromethyl)ethenyl boronic acid was conveniently prepared from the reaction of readily available 2-bromotrifluoropropene with alkyl berate and magnesium in one-pot. This boronic acid can undergo palladium-catalyse d coupling reactions with aryl halides to afford a series of useful alpha-( trifluoromethyl)styrene derivatives in high yield. (C) 2001 Elsevier Scienc e Ltd. All rights reserved.