An efficient asymmetric aldol reaction of Chan's diene promoted by chiral Ti(IV)-BINOL complex

Authors
Soriente, A De Rosa, M Stanzione, M Villano, R Scettri, A
Citation
A. Soriente et al., An efficient asymmetric aldol reaction of Chan's diene promoted by chiral Ti(IV)-BINOL complex, TETRAHEDR-A, 12(6), 2001, pp. 959-963
Citations number
17
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166 → ACNP
Volume
12
Issue
6
Year of publication
2001
Pages
959 - 963
Database
ISI
SICI code
0957-4166(20010417)12:6<959:AEAARO>2.0.ZU;2-Y
Abstract
1.3-Bis-(trimethylsilyloxy)-1-methoxy-buta-1,3-diene (Chan's diene) can be conveniently used in asymmetric aldol reaction with aromatic, heteroaromati c, alpha,beta -unsaturated and aliphatic aldehydes in the presence of catal ytic amounts (2-8% mol) of chiral Ti(IV)/(R)-BINOL complex. (C) 2001 Elsevi er Science Ltd. All rights reserved.