Renal cell carcinoma detected in a cadaveric donor after orthotopic liver and contralateral renal transplantation in two recipients

Background. Although rare, renal cell carcinoma has been found during renal recovery for cadaveric organ transplantation, Previously, we reported this incidence to be 0.9%. In one cadaveric donor, the lives and left kidney ha d been transplanted before the discovery of renal cell carcinoma (T1) in th e right kidney. Methods, We retrospectively reviewed the medical records of two patients wh o had received cadaveric allografts from a donor with a known renal cell ca rcinoma. Results. Both patients have been followed for 4 years with blood chemistrie s and chest x-ray every 3 months for year I, every 4 months for years 2 and 3, and every 6 months thereafter They also underwent allograft ultrasound every 6 months and an annual CT scan of the abdomen. Both patients have sho wn no evidence of metastatic disease throughout their follow-up. Discussion. In the rare instance that a patient receives an organ from a ca daveric donor with a known renal cell carcinoma, it is mandatory to follow these patients closely observing for both allograft recurrence and metastat ic disease.