The social-emotional characteristics and drug-use patterns of adolescents w
ho reported having no friends (i.e., isolates) were compared to those of ad
olescents in drug-using and non-drug-using peer groups. Adolescents who did
not have drug-using peers reported the lowest drug use and those with drug
-using peers had the highest drug use, with adolescents who were isolated f
alling in between. Isolated youth reported more shyness, greater feelings o
f alienation, and lower social acceptance than did those in the other group
s. Isolated youth also reported more anger and depression than did youth wi
th non-drug-using peers, but less anger and equivalent depression when comp
ared to adolescents with drug-using peers. Results are discussed in terms o
f social-emotional characteristics of isolated youth and risk/protective fa
ctors.