INSECTICIDAL ROCAGLAMIDE DERIVATIVES FROM AGLAIA-ELLIPTICA AND AGLAIA-HARMSIANA

Fruits of Aglaia elliptica and leaves of A. harmsiana yielded seven in secticidal rocaglamide derivatives including five components which pro ved to be new natural products. Structure elucidation of the new compo unds is described. All rocaglamide derivatives isolated exhibited stro ng insecticidal activity towards neonate larvae of the polyphagous pes t insect Spodoptera littoralis when incorporated into an artificial di et with LC50 values varying from 0.8-19.7 ppm. The known didesmethylro caglamide was the most active compound encountered. Its LC50 (0.8 ppm) and EC50 (0.05 ppm) were identical to those of azadirachtin which was included as a positive control. (C) 1997 Elsevier Science Ltd. All ri ghts reserved.