Objectives: For more than three decades there has been speculation regardin
g a possible role of zoonotic diseases in the development of human leukemia
. This study investigated the potential relationship between exposure to pe
ts and the development of childhood leukemia.
Methods: Data from 2359 cases of acute leukemia from two large case-control
studies were analyzed. Cases were individually matched to population contr
ols on telephone exchange, age, and race. Conditional logistic regression w
as used to estimate odds ratios (OR) associated with pet ownership.
Results: Overall, there was no association between pet ownership (either "a
ny pet", dog, or cat) and childhood acute leukemia (ORany pet:=1.01, 95% CI
0.89-1.2). Additionally, no relationship was found between exposure to an
ill pet and childhood leukemia.
Conclusion: The results of this analysis suggest that pet ownership (health
y or sick) is unrelated to an increased risk of childhood leukemia.