Metabolic engineering as an integrating platform for strain development

Authors
Stafford, DE Stephanopoulos, G
Citation
De. Stafford et G. Stephanopoulos, Metabolic engineering as an integrating platform for strain development, CURR OPIN M, 4(3), 2001, pp. 336-340
Citations number
48
Categorie Soggetti
Biotecnology & Applied Microbiology",Microbiology
Journal title
CURRENT OPINION IN MICROBIOLOGY
ISSN journal
13695274 → ACNP
Volume
4
Issue
3
Year of publication
2001
Pages
336 - 340
Database
ISI
SICI code
1369-5274(200106)4:3<336:MEAAIP>2.0.ZU;2-S
Abstract
Integration of the analytical framework and experimental tools of metabolic engineering with emerging technologies such as DNA microarrays and directe d evolution stands to dramatically improve the approaches by which strain i mprovement and biocatalyst design are pursued in the future. Progress in ge nomics and applied molecular biology, together with increasing emphasis on renewable resource utilization for chemical production, has advanced metabo lic engineering to the forefront of biotechnological interest.