Kawasaki syndrome in an adult: Case report and review of the literature inadolescents and adults

Kawasaki syndrome in adults is very rare, with fewer than 50 cases reported in the English-language literature. We describe the ease of a physician wi th Kawasaki syndrome and summarize the clinical features and treatment of I I patients in the literature since the last review in 1994. Our patient pre sented with high fever, conjunctivitis, and arthralgias, then developed pro gressive toxicity with oral lesions, cervical adenopathy, and desquamation of the fingers and toes. No exanthematous rash or coronary artery aneurysms were found. Recovery was rapid after therapy with aspirin and intravenous immunoglobulin (IVIg). The diagnosis of Kawasaki syndrome depends on clinical criteria and the exc lusion of other diseases. This diagnosis can be challenging to make in an a dult, particularly when it presents without all typical features. Kawasaki syndrome must be considered nonetheless in an adult with unexplained fever of more than 5 days duration, because early diagnosis and combination thera py with aspirin and IVIg can prevent the Life-threatening complication of c oronary artery aneurysms.