Mf. Grunebaum et al., Medication supervision and adherence of persons with psychotic disorders in residential treatment settings: A pilot study, J CLIN PSY, 62(5), 2001, pp. 394-399
Background: Little is known about risk factors for and predictors of medica
tion nonadherence within residential facilities. This pilot study examined
the association between medication adherence and level of supervision and o
ther environmental and clinical variables among patients with schizophrenia
and related psychotic disorders living in supported housing.
Method: A convenience sample of 74 adult residents with schizophrenia and r
elated psychotic disorders (DSM-IV criteria) living in 4 supported housing
facilities in New York City were assessed by their treating psychiatrist fo
r medication cessation during the previous month. Demographic characteristi
cs, medications, supervision, global function as measured by the Global Ass
essment of Functioning (GAF), and substance abuse were also assessed. A pri
ori hypotheses were that regimen complexity would be directly and medicatio
n supervision would be inversely related to medication nonadherence.
Results: In multivariate models, lack of direct medication supervision, neg
ative medication attitude, and lower GAF score were associated with increas
ed medication nonadherence in the recent past.
Conclusion: This pilot study suggests that direct supervision of medication
is associated with better adherence in residential treatment settings. Thi
s finding is relevant for mental health service planners and clinicians wor
king in these settings.