An important component of metabolic regulation is compartmentation and spec
ialization. Subcellular compartmentation and the role of individual organel
les is well studied, though less consideration has been given to the extent
to which organelles differ between cells. Organelles extracted from whole
tissue homogenates will have generally originated from a range of cell type
s. This review describes and assesses the regulation of metabolic activity
in plants at both the cellular and subcellular level by considering special
ization of mitochondria and plastids.