MICROWAVE CO2 PLASMA-INITIATED VAPOR-PHASE GRAFT-POLYMERIZATION OF ACRYLIC-ACID ONTO POLYTETRAFLUOROETHYLENE FOR IMMOBILIZATION OF HUMAN THROMBOMODULIN

Authors
VASILETS VN HERMEL G KONIG U WERNER C MULLER M SIMON F GRUNDKE K IKADA Y JACOBASCH HJ
Citation
Vn. Vasilets et al., MICROWAVE CO2 PLASMA-INITIATED VAPOR-PHASE GRAFT-POLYMERIZATION OF ACRYLIC-ACID ONTO POLYTETRAFLUOROETHYLENE FOR IMMOBILIZATION OF HUMAN THROMBOMODULIN, Biomaterials, 18(17), 1997, pp. 1139-1145
Citations number
17
Categorie Soggetti
Engineering, Biomedical","Materials Science, Biomaterials
Journal title
Biomaterials → ACNP
ISSN journal
01429612
Volume
18
Issue
17
Year of publication
1997
Pages
1139 - 1145
Database
ISI
SICI code
0142-9612(1997)18:17<1139:MCPVGO>2.0.ZU;2-5
Abstract
The functionalization of polytetrafluoroethylene (PTFE) for human thro mbomodulin (hTM) binding has been achieved by CO2 plasma activation an d subsequent vapour phase graft polymerization of acrylic acid (AA). T he PTFE surfaces after CO2 plasma treatment, AA grafting and hTM immob ilization were characterized by attenuated total reflection Fourier tr ansform infrared (ATR-FTIR) spectroscopy, X-ray photoelectron spectros copy (XPS) and electron spin resonance (ESR) spectroscopy, as well as by zeta potential and wetting measurements to quantitatively control e ach step of modification. The activity of immobilized hTM was estimate d by the protein C activation test. (C) 1997 Elsevier Science Limited. All rights reserved.