The authors report the findings of two patients that confirm the location o
f the horizontal meridian in the human visual cortex. The first patient had
an inferior quadrant defect with a band of horizontal meridian sparing. Ma
gnetic resonance imaging showed a lesion concentrated along the medial stri
ate cortex. The second patient had a homonymous horizontal defect that resu
lted from removal of an arteriovenous malformation located in the lateral s
triate cortex, The findings of these two patients demonstrate that the hori
zontal meridian is represented at the calcarine fissure base in the primary
visual cortex.