Is daily data collection of sexual and other health-related behaviors react
ive? This question was examined by exploring trends in daily reports of sex
ual intercourse, condom use, drinking. smoking, and vegetable and fruit con
sumption over a 2-month period. The trends were examined for evidence of fa
tigue effects and socially desirable responding. The effects of data collec
tion method and gender were also examined. Results from a hierarchical line
ar modeling analysis showed a significant trend toward decreased reporting
of drinking, smoking, and sexual intercourse, bur no significant trends in
fruit and vegetable consumption or condom use. These patterns are not consi
stent with fatigue effects or socially desirable responding. The results ar
e discussed in relation to choosing data collection methods that minimize e
rror.