Pseudo-first order rate constants and thermodynamic parameters for esters hydrolysis in neutral medium

A comprehensive study of the Pseudo-first order rate constants K-0 (sec(-1) ) for uncatalysed reaction and the thermodynamic parameters for alkyl forma tes HCOOR in neutral medium in the temperature range (293-343 K) has been u ndertaken The fi ee energies, enthalpies and entropies of activation were m easured according to the theory of absolute reaction rates. The enthalpies and entropies of activation decreased from methyl to ethyl formates whereas the DeltaS(#) and DeltaH(#) values obtained for isopropyl formate were app roximately the same as that for ethyl formate indicating that further subst itution at the proportional to -C atom did not produce any further signific ant intramolecular polarization. The A(AL)1 mechanism was operative in neut ral hydrolysis of esters.