A prospective study of the safety and efficacy of suprapubic transvesical prostatectomy in patients with benign prostatic hyperplasia

Purpose: We investigate the safety and efficacy of suprapubic transvesical prostatectomy, and the change in bladder wall thickness after surgery. Materials and Methods: We conducted a prospective 1 center study of 32 cons ecutive patients who underwent transvesical prostatectomy from December 199 6 to March 1997 for benign prostatic hyperplasia with large prostate volume , who were followed for I year. Pressure flow study and transrectal sonogra phy were performed at baseline and repeated at 6 months. Bladder wall thick ness was measured at baseline and regular intervals postoperatively. A morb idity questionnaire was completed during the first 6 weeks after surgery. Results: An average of 63 gm. prostate adenoma were enucleated at surgery. An indwelling catheter was required for an average plus or minus standard d eviation of 5.4 +/- 2.6 days after treatment. The International Prostate Sy mptom Score decreased from 19.9 +/- 4.4 to 1.5 +/- 2.7 and the quality of l ife score decreased from 4.9 +/- 1.0 to 0.2 +/- 0.4 at year 1, respectively . Maximum flow rate improved from 9.1 +/- 5.3 to 29.0 +/- 8.9 ml. per secon d. Residual urine decreased from 128 +/- 113 to 8 +/- 18 ml. Before surgery 30 patients had obstruction and 2 were in the equivocal zone of the Intern ational Continence Society nomogram. At 6 months after prostatectomy 30 pat ients did not have obstruction, and 2 who were subsequently operated on for bladder neck sclerosis were equivocal and had obstruction, respectively. N o patient had significant postoperative bleeding and no heterologous blood transfusions were required. There were 4 men who had urinary tract; infecti on and 1 who had wound infection. A slight decrease in erectile function wa s observed 6 weeks postoperatively, and no change in patient libido and qua lity of sex life was reported. The total complication rate was 31.3%. The b ladder was unstable in 7 men before and 3 after surgery. A significant decr ease in bladder wall thickness was observed from 5.2 +/- 0.7 at baseline to 2.9 +/- 0.9 mm. at year 1 postoperatively. Conclusions: Our study confirms the excellent clinical outcome of transvesi cal prostatectomy, and rapid improvement of most subjective and objective p arameters during the 4 weeks after surgery. Bladder hypertrophy appears to be significantly reduced after prostate surgery. The urodynamic results in patients who underwent open surgery probably represent the maximum obtainab le relief of obstruction and should be considered the reference standard to which all other treatments, including transurethral resection, should aspi re.