The human gene map for performance and health-related fitness phenotypes

Citation
T. Rankinen et al., The human gene map for performance and health-related fitness phenotypes, MED SCI SPT, 33(6), 2001, pp. 855-867
Citations number
65
Categorie Soggetti
Medical Research General Topics
Journal title
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
ISSN journal
01959131 → ACNP
Volume
33
Issue
6
Year of publication
2001
Pages
855 - 867
Database
ISI
SICI code
0195-9131(200106)33:6<855:THGMFP>2.0.ZU;2-C
Abstract
The aim of this paper is to describe the first human gene map for physical performance and health-related fitness traits based on the papers published until the end of 2000. Studies of candidate genes using case-control and o ther designs are reviewed. Quantitative trait loci from the limited evidenc e reported to date in genomic scans are also incorporated. Performance and fitness phenotypes in the sedentary state as well as their changes during e xercise, if applicable, or in response to exercise training are considered. Physical performance traits include cardiorespiratory endurance indicators and muscular strength or muscular performance variables. Health-related fi tness phenotypes are grouped under the following categories: hemodynamic tr aits; anthropometry and body composition; insulin and glucose metabolism; a nd Lipids, lipoproteins, and hemostatic factors. A yearly update of this hu man gene map will be published.