Adenosquamous carcinoma of the colorectum: Report of two cases

Adenosquamous carcinomas of the colorectum are rare neoplasms. Our experien ce with two cases is presented in this paper. One patient, who complained o f bloody stool, was found to have adenocarcinoma in the sigmoid colon. He r eceived a laparoscopy-assisted sigmoidectomy. The histological examination revealed that the tumor was adenosquamous carcinoma. To date, he has surviv ed six months post operatively without evidence of recurrence. The other pa tient, who complained of anal bleeding, was found to have rectal adenocarci noma and received a low anterior resection. Histological examination reveal ed that the tumor was an adenosquamous carcinoma. He remains alive, with no evidence of recurrence, nine years post operatively. Both cases showed par acolic lymph node metastasis. Because of its very low incidence, the histog enesis, malignancy and prognosis of this disease remain unclear. Thus, furt her clinical and histological study of this disease entity is required.