A technique of heterotopic, infrarenal heart transplantation with double anastomosis in mice

Authors
Doenst, T Schlensak, C Kobba, JL Beyersdorf, F
Citation
T. Doenst et al., A technique of heterotopic, infrarenal heart transplantation with double anastomosis in mice, J HEART LUN, 20(7), 2001, pp. 762-765
Citations number
9
Categorie Soggetti
Cardiovascular & Respiratory Systems
Journal title
JOURNAL OF HEART AND LUNG TRANSPLANTATION
ISSN journal
10532498 → ACNP
Volume
20
Issue
7
Year of publication
2001
Pages
762 - 765
Database
ISI
SICI code
1053-2498(200107)20:7<762:ATOHIH>2.0.ZU;2-V
Abstract
Mouse heart transplantation is frequently used to investigate mechanisms of rejection and immune response. A fully vascularized technique is presented in which the graft ascending aorta is anastomosed end-to-side to the recip ient's aorta and the pulmonary aorta is anastomosed end-to-side to the infe rior vena cava using 11-0 Ethilon suture, We suggest that this double anast omosis technique is a valuable tool to investigate immune mechanisms in mic e.